The Carolina Panthers and Buffalo Bills will square off in a preseason matchup with unusual significance on Saturday. The game marks the inaugural contest at Buffalo’s renovated Highmark Stadium in Orchard Park, New York, and both teams have committed to fielding their starting lineups, offering fans a genuine preview of their offensive and defensive units rather than the typical preseason rotation of reserves.
Carolina has released its unofficial depth chart ahead of the contest. Bryce Young heads the quarterback rotation, with Kenny Pickett serving as his backup. Running back duties will fall primarily to Chuba Hubbard, though he is currently dealing with a hamstring injury that has him listed as week-to-week. Jonathon Brooks slots in as the secondary option at the position, giving the Panthers depth at a critical skill position.
The Panthers’ receiving corps features Tetairoa McMillan, Jalen Coker, and Xavier Legette as the top three wide receivers, while Tommy Tremble anchors the tight end position. Defensively, the team will rely on Derrick Brown, Cam Jackson, and Bobby Brown III along the defensive line, with Devin Lloyd and Trevin Wallace leading the interior linebacker group. The secondary pairing of Jaycee Horn and Mike Jackson will anchor the cornerback positions.
With both teams planning to deploy their starters in an otherwise low-stakes preseason affair, this matchup presents an opportunity for coaches to evaluate how their first-string units function in live game action before the regular season begins.
