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Researchers have identified a fungus naturally present in the human gut that may offer protection against radiation damage, according to a recent study published in PNAS. Scientists from China investigated Mucor racemosus, a symbiotic organism already inhabiting our digestive systems, and discovered it possesses unexpected radioprotective properties that could have significant health implications.
In laboratory experiments with mice, animals treated with M. racemosus showed markedly improved outcomes after radiation exposure compared to untreated control groups. The fungus-treated subjects experienced reduced weight loss, lower inflammation levels, and decreased oxidative stress. Researchers identified multiple mechanisms behind this protective effect, including three amino acids—L-glutamic acid, L-aspartic acid, and DL-lysine—that the fungus produces to facilitate DNA repair and tissue recovery. Additionally, another compound called methylthioadenosine enhanced radiation protection by altering beneficial gut bacteria behavior.
To explore practical applications, the team fed irradiated mice cheese fermented with M. racemosus. Results showed significant improvements in intestinal health and reduced inflammatory markers compared to mice consuming unfermented cheese. The fungus is already present in some fermented foods and holds FDA approval for dietary consumption, though scientists emphasize that individuals with compromised immune systems should avoid it.
While the findings suggest promising therapeutic potential, researchers caution that extensive additional investigation is necessary before recommending M. racemosus for widespread medical or dietary use. The study highlights fungi as underutilized components of the human microbiota with potential applications for mitigating radiation-related health conditions.
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It already lives inside you.